Detection of Heart Shunts by Means of 125-i.

Prinzmetal et a!, used 24Na for this purpose (1), while others used al bumin 1311 (2). With more extensive experience, procedures improved over the years until, in 1958, Pritchard et al (3) reported an effective method for the external precordial detection and determination of cardiac output with albumin †̃@†̃I. During this time, a good correlation with dye dilution technique by means of arterial puncture was also noted. Later, Vernejoul (4) used 1321for this same purpose.